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causes of diabetes mellitus
(IN suh lin AH spart)
NovoLog

What is the most important information I should know about insulin aspart?
• Know the signs and symptoms of low blood sugar (hypoglycemia), whichinclude headache, drowsiness, weakness, dizziness, fast heartbeat, sweating,tremor, and nausea causes of diabetes mellitus. Carry a piece of candy or glucose tablets with you to treatepisodes of low blood sugar causes of diabetes mellitus.
• Follow any diet and exercise plan that you have developed with your doctoror nurse causes of diabetes mellitus. Changes in what you eat or how much you exercise can change the amountof insulin that you need to control blood sugar levels causes of diabetes mellitus.
• Ask your doctor or nurse what to do if you are sick with a cold, flu,or fever causes of diabetes mellitus. These illnesses may change your insulin requirements causes of diabetes mellitus.
• Insulin aspart differs from regular human insulin by how quickly it beginsto work and the amount of time it continues to be effective causes of diabetes mellitus. Because insulinaspart begins to work soon after it is injected, the injection of insulin aspartshould immediately be followed by a meal causes of diabetes mellitus. Because of the short amount of timethat insulin aspart continues to be effective, a longer-acting insulin may alsobe required causes of diabetes mellitus.
• Do not change the brand of insulin aspart or syringe that you are usingwithout first talking to your doctor or pharmacist causes of diabetes mellitus. Some brands of insulin aspartand syringes are interchangeable, while others are not causes of diabetes mellitus. Your doctor and/or pharmacistknow which brands can be substituted for one another causes of diabetes mellitus.


What is insulin aspart?
• Insulin is a hormone naturally produced by the pancreas causes of diabetes mellitus. Insulin enablesthe body to use the sugar in food as a source of energy causes of diabetes mellitus. When the body doesnot produce enough insulin, or when the insulin produced by the body is noteffective enough, the condition is called diabetes mellitus causes of diabetes mellitus. This conditionallows sugar levels in the blood to become very high causes of diabetes mellitus. Diabetics must use man-madeinsulin or insulin that comes from pigs (which is very similar to human insulin)to lower these high blood sugar levels causes of diabetes mellitus.
• There are three types of insulin, which differ in how soon they beginto work and how long their effects last causes of diabetes mellitus. Insulin aspart is one type of insulinthat begins to work very quickly and its effects that last for approximately3 to 5 hours causes of diabetes mellitus. Insulin aspart is usually used in combination with another longer-actinginsulin causes of diabetes mellitus.
• Insulin aspart may also be used for purposes other than those listedin this medication guide causes of diabetes mellitus.


What should I discuss with my healthcare provider before using insulin aspart?
• Do not use insulin aspart if you are allergic to insulin or if you havean intolerance of a certain insulin aspart product causes of diabetes mellitus.
• Before using insulin aspart, tell your doctor if you have kidney or liverdisease causes of diabetes mellitus. You may require a dosage adjustment or special monitoring during treatment causes of diabetes mellitus.
• Insulin aspart is in the FDA pregnancy category C causes of diabetes mellitus. This means that itis not known whether it will be harmful to an unborn baby causes of diabetes mellitus. Do not use this medicationwithout first talking to your doctor if you are pregnant or could become pregnantduring treatment causes of diabetes mellitus.
• It is not known whether insulin aspart passes into breast milk causes of diabetes mellitus. Do notuse this medication without first talking to your doctor if you are breast-feedinga baby causes of diabetes mellitus.


How should I use insulin aspart?
• Use insulin aspart exactly as directed by your doctor causes of diabetes mellitus. If you do notunderstand these instructions, ask your doctor, nurse, or pharmacist to explainthem to you causes of diabetes mellitus.
• Insulin aspart differs from regular human insulin by how quickly it beginsto work and the amount of time it continues to be effective causes of diabetes mellitus. Because insulinaspart begins to work soon after it is injected, the injection of insulin aspartshould immediately be followed by a meal causes of diabetes mellitus. Because of the short amount of timethat insulin aspart continues to be effective, a longer-acting insulin may alsobe required causes of diabetes mellitus.
• Insulin aspart is usually used immediately before a meal (a meal shouldbe started within 5 to 10 minutes after injecting the medication) causes of diabetes mellitus. Follow yourdoctor's instructions causes of diabetes mellitus.
• Rotate injection sites as directed by your doctor causes of diabetes mellitus. Usually, you shouldnot inject within 1 inch of the same site within 1 month causes of diabetes mellitus.
• Never reuse a needle or syringe causes of diabetes mellitus. The syringes used must not contain anyother medicinal product or residue causes of diabetes mellitus. Dispose of all needles and syringes in anappropriate, puncture-resistant disposal container causes of diabetes mellitus.
• Do not change the insulin strength (e.g., U-100) or insulin type (e.g.,aspart) unless your doctor recommends a change for you causes of diabetes mellitus.
• Do not change the brand of insulin aspart or syringe that you are usingwithout first talking to your doctor or pharmacist causes of diabetes mellitus. Some brands of insulin andsyringes are interchangeable, while others are not causes of diabetes mellitus. Your doctor and/or pharmacistknow which brands can be substituted for one another causes of diabetes mellitus.
• Follow any diet and exercise plan that you have developed with your doctoror nurse causes of diabetes mellitus. Changes in what you eat or how much you exercise can change the amountof insulin that you need to control blood sugar levels causes of diabetes mellitus.
• Ask your doctor or nurse what to do if you are sick with a cold, flu,or fever causes of diabetes mellitus. These illnesses may change your insulin requirements causes of diabetes mellitus.
• Wear some type of medical identification bracelet, necklace, or otheralert tag to inform others that you have diabetes and that you require insulinin the case of an emergency causes of diabetes mellitus.
• To adequately control diabetes, proper foot care, eye care, dental care,and overall proper health care are necessary causes of diabetes mellitus. Visit your doctor, dentist, eyedoctor, and other heath care practitioners as recommended by your doctor causes of diabetes mellitus.
• Do not use any insulin that is discolored, looks thick, has particlesin it, or looks different from your previous bottles or cartridges of insulinaspart causes of diabetes mellitus.
• Store unopened bottles and cartridges of insulin aspart in the refrigeratorbetween 36 and 46 degrees Fahrenheit (2 and 8 degrees Celsius) causes of diabetes mellitus. Do not storeinsulin aspart in the freezer and do not allow it to freeze causes of diabetes mellitus. Do not use insulinaspart if it has been frozen causes of diabetes mellitus. Throw away any expired insulin aspart causes of diabetes mellitus.
• Vials or cartridges of insulin aspart in use can be kept unrefrigeratedat room temperature, below 86 degrees Fahrenheit (30 degrees Celsius), for upto 28 days but should not be exposed to excessive heat or sunlight causes of diabetes mellitus.


What happens if I miss a dose?
• Follow your doctor's directions if you miss a dose of insulin causes of diabetes mellitus. To preventmissed doses, be sure to always have enough insulin on hand, especially if youare going on vacation causes of diabetes mellitus.


What happens if I overdose?
• Seek emergency medical attention causes of diabetes mellitus.
• Symptoms of an insulin overdose reflect very low blood sugar levels andinclude headache, irregular heartbeat, increased heart rate or pulse, sweating,tremor, nausea, increased hunger, and anxiety causes of diabetes mellitus.


What should I avoid while using insulin aspart?
• Do not use alcohol without first talking to your doctor causes of diabetes mellitus. It lowers bloodsugar, and you may experience dangerously low blood sugar levels causes of diabetes mellitus.
• Follow any diet and exercise plan that you have developed with your doctoror nurse causes of diabetes mellitus. Changes in what you eat or how much you exercise can change the amountof insulin that you need to control blood sugar levels causes of diabetes mellitus.


What are the possible side effects of insulin aspart?
• Rarely, people have allergic reactions to insulin causes of diabetes mellitus. Seek emergency medicalattention if you experience an allergic reaction (difficulty breathing; closingof your throat; swelling of your lips, tongue, or face; or hives) causes of diabetes mellitus.
• The side effects of insulin therapy result mostly from blood sugar levelsthat are either too high or too low causes of diabetes mellitus. You should be familiar with the symptomsof both high and low blood sugar levels and know how to treat both conditions causes of diabetes mellitus. Also, be sure your family and close friends know how to help you in an emergency causes of diabetes mellitus.
• Low blood sugar may occur when too much insulin is used; when meals aremissed or delayed; if you exercise more than usual; during illness, especiallywith vomiting or diarrhea; if you take other medications; after drinking alcohol;and in other situations causes of diabetes mellitus.
• Hypoglycemia, or low blood sugar, has the following symptoms: shaking,headache, cold sweats, pale, cool skin, anxiety, and difficulty concentrating causes of diabetes mellitus.
• Keep sugary candy; fruit juice; or glucose tablets on hand to treat episodesof low blood sugar causes of diabetes mellitus.
• Increased blood sugar may occur if not enough insulin is used, if youeat significantly more food then usual, if you exercise less than usual, ifyou take other medications, if you have a fever or other illness, and in othersituations causes of diabetes mellitus.
• Hyperglycemia, or high blood sugar, has the following symptoms: increasedthirst, increased hunger, and increased urination causes of diabetes mellitus.
• Monitor your blood sugar levels and ask your doctor how to adjust yourinsulin doses if your blood sugar levels are too high causes of diabetes mellitus.
• Side effects may also occur at the site of injection causes of diabetes mellitus. If the area becomesthickened, hard, or pitted, talk to your doctor before injecting at that siteagain causes of diabetes mellitus.
• Side effects other than those listed here may also occur causes of diabetes mellitus. Talk to yourdoctor about any side effect that seems unusual or that is especially bothersome causes of diabetes mellitus.


What other drugs will affect insulin aspart?
• Many drugs can interact with insulin or affect blood sugar levels causes of diabetes mellitus. Donot take any other medicines, including prescription products or over-the-countermedicines or supplements, without first talking to your doctor or pharmacistduring treatment with insulin causes of diabetes mellitus.


Where can I get more information?
• Your pharmacist has additional information about insulin aspart writtenfor health professionals that you may read causes of diabetes mellitus.


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