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e coli for insulin production
(IN suh lin AH spart)
NovoLog

What is the most important information I should know about insulin aspart?
• Know the signs and symptoms of low blood sugar (hypoglycemia), whichinclude headache, drowsiness, weakness, dizziness, fast heartbeat, sweating,tremor, and nausea e coli for insulin production. Carry a piece of candy or glucose tablets with you to treatepisodes of low blood sugar e coli for insulin production.
• Follow any diet and exercise plan that you have developed with your doctoror nurse e coli for insulin production. Changes in what you eat or how much you exercise can change the amountof insulin that you need to control blood sugar levels e coli for insulin production.
• Ask your doctor or nurse what to do if you are sick with a cold, flu,or fever e coli for insulin production. These illnesses may change your insulin requirements e coli for insulin production.
• Insulin aspart differs from regular human insulin by how quickly it beginsto work and the amount of time it continues to be effective e coli for insulin production. Because insulinaspart begins to work soon after it is injected, the injection of insulin aspartshould immediately be followed by a meal e coli for insulin production. Because of the short amount of timethat insulin aspart continues to be effective, a longer-acting insulin may alsobe required e coli for insulin production.
• Do not change the brand of insulin aspart or syringe that you are usingwithout first talking to your doctor or pharmacist e coli for insulin production. Some brands of insulin aspartand syringes are interchangeable, while others are not e coli for insulin production. Your doctor and/or pharmacistknow which brands can be substituted for one another e coli for insulin production.


What is insulin aspart?
• Insulin is a hormone naturally produced by the pancreas e coli for insulin production. Insulin enablesthe body to use the sugar in food as a source of energy e coli for insulin production. When the body doesnot produce enough insulin, or when the insulin produced by the body is noteffective enough, the condition is called diabetes mellitus e coli for insulin production. This conditionallows sugar levels in the blood to become very high e coli for insulin production. Diabetics must use man-madeinsulin or insulin that comes from pigs (which is very similar to human insulin)to lower these high blood sugar levels e coli for insulin production.
• There are three types of insulin, which differ in how soon they beginto work and how long their effects last e coli for insulin production. Insulin aspart is one type of insulinthat begins to work very quickly and its effects that last for approximately3 to 5 hours e coli for insulin production. Insulin aspart is usually used in combination with another longer-actinginsulin e coli for insulin production.
• Insulin aspart may also be used for purposes other than those listedin this medication guide e coli for insulin production.


What should I discuss with my healthcare provider before using insulin aspart?
• Do not use insulin aspart if you are allergic to insulin or if you havean intolerance of a certain insulin aspart product e coli for insulin production.
• Before using insulin aspart, tell your doctor if you have kidney or liverdisease e coli for insulin production. You may require a dosage adjustment or special monitoring during treatment e coli for insulin production.
• Insulin aspart is in the FDA pregnancy category C e coli for insulin production. This means that itis not known whether it will be harmful to an unborn baby e coli for insulin production. Do not use this medicationwithout first talking to your doctor if you are pregnant or could become pregnantduring treatment e coli for insulin production.
• It is not known whether insulin aspart passes into breast milk e coli for insulin production. Do notuse this medication without first talking to your doctor if you are breast-feedinga baby e coli for insulin production.


How should I use insulin aspart?
• Use insulin aspart exactly as directed by your doctor e coli for insulin production. If you do notunderstand these instructions, ask your doctor, nurse, or pharmacist to explainthem to you e coli for insulin production.
• Insulin aspart differs from regular human insulin by how quickly it beginsto work and the amount of time it continues to be effective e coli for insulin production. Because insulinaspart begins to work soon after it is injected, the injection of insulin aspartshould immediately be followed by a meal e coli for insulin production. Because of the short amount of timethat insulin aspart continues to be effective, a longer-acting insulin may alsobe required e coli for insulin production.
• Insulin aspart is usually used immediately before a meal (a meal shouldbe started within 5 to 10 minutes after injecting the medication) e coli for insulin production. Follow yourdoctor's instructions e coli for insulin production.
• Rotate injection sites as directed by your doctor e coli for insulin production. Usually, you shouldnot inject within 1 inch of the same site within 1 month e coli for insulin production.
• Never reuse a needle or syringe e coli for insulin production. The syringes used must not contain anyother medicinal product or residue e coli for insulin production. Dispose of all needles and syringes in anappropriate, puncture-resistant disposal container e coli for insulin production.
• Do not change the insulin strength (e.g., U-100) or insulin type (e.g.,aspart) unless your doctor recommends a change for you e coli for insulin production.
• Do not change the brand of insulin aspart or syringe that you are usingwithout first talking to your doctor or pharmacist e coli for insulin production. Some brands of insulin andsyringes are interchangeable, while others are not e coli for insulin production. Your doctor and/or pharmacistknow which brands can be substituted for one another e coli for insulin production.
• Follow any diet and exercise plan that you have developed with your doctoror nurse e coli for insulin production. Changes in what you eat or how much you exercise can change the amountof insulin that you need to control blood sugar levels e coli for insulin production.
• Ask your doctor or nurse what to do if you are sick with a cold, flu,or fever e coli for insulin production. These illnesses may change your insulin requirements e coli for insulin production.
• Wear some type of medical identification bracelet, necklace, or otheralert tag to inform others that you have diabetes and that you require insulinin the case of an emergency e coli for insulin production.
• To adequately control diabetes, proper foot care, eye care, dental care,and overall proper health care are necessary e coli for insulin production. Visit your doctor, dentist, eyedoctor, and other heath care practitioners as recommended by your doctor e coli for insulin production.
• Do not use any insulin that is discolored, looks thick, has particlesin it, or looks different from your previous bottles or cartridges of insulinaspart e coli for insulin production.
• Store unopened bottles and cartridges of insulin aspart in the refrigeratorbetween 36 and 46 degrees Fahrenheit (2 and 8 degrees Celsius) e coli for insulin production. Do not storeinsulin aspart in the freezer and do not allow it to freeze e coli for insulin production. Do not use insulinaspart if it has been frozen e coli for insulin production. Throw away any expired insulin aspart e coli for insulin production.
• Vials or cartridges of insulin aspart in use can be kept unrefrigeratedat room temperature, below 86 degrees Fahrenheit (30 degrees Celsius), for upto 28 days but should not be exposed to excessive heat or sunlight e coli for insulin production.


What happens if I miss a dose?
• Follow your doctor's directions if you miss a dose of insulin e coli for insulin production. To preventmissed doses, be sure to always have enough insulin on hand, especially if youare going on vacation e coli for insulin production.


What happens if I overdose?
• Seek emergency medical attention e coli for insulin production.
• Symptoms of an insulin overdose reflect very low blood sugar levels andinclude headache, irregular heartbeat, increased heart rate or pulse, sweating,tremor, nausea, increased hunger, and anxiety e coli for insulin production.


What should I avoid while using insulin aspart?
• Do not use alcohol without first talking to your doctor e coli for insulin production. It lowers bloodsugar, and you may experience dangerously low blood sugar levels e coli for insulin production.
• Follow any diet and exercise plan that you have developed with your doctoror nurse e coli for insulin production. Changes in what you eat or how much you exercise can change the amountof insulin that you need to control blood sugar levels e coli for insulin production.


What are the possible side effects of insulin aspart?
• Rarely, people have allergic reactions to insulin e coli for insulin production. Seek emergency medicalattention if you experience an allergic reaction (difficulty breathing; closingof your throat; swelling of your lips, tongue, or face; or hives) e coli for insulin production.
• The side effects of insulin therapy result mostly from blood sugar levelsthat are either too high or too low e coli for insulin production. You should be familiar with the symptomsof both high and low blood sugar levels and know how to treat both conditions e coli for insulin production. Also, be sure your family and close friends know how to help you in an emergency e coli for insulin production.
• Low blood sugar may occur when too much insulin is used; when meals aremissed or delayed; if you exercise more than usual; during illness, especiallywith vomiting or diarrhea; if you take other medications; after drinking alcohol;and in other situations e coli for insulin production.
• Hypoglycemia, or low blood sugar, has the following symptoms: shaking,headache, cold sweats, pale, cool skin, anxiety, and difficulty concentrating e coli for insulin production.
• Keep sugary candy; fruit juice; or glucose tablets on hand to treat episodesof low blood sugar e coli for insulin production.
• Increased blood sugar may occur if not enough insulin is used, if youeat significantly more food then usual, if you exercise less than usual, ifyou take other medications, if you have a fever or other illness, and in othersituations e coli for insulin production.
• Hyperglycemia, or high blood sugar, has the following symptoms: increasedthirst, increased hunger, and increased urination e coli for insulin production.
• Monitor your blood sugar levels and ask your doctor how to adjust yourinsulin doses if your blood sugar levels are too high e coli for insulin production.
• Side effects may also occur at the site of injection e coli for insulin production. If the area becomesthickened, hard, or pitted, talk to your doctor before injecting at that siteagain e coli for insulin production.
• Side effects other than those listed here may also occur e coli for insulin production. Talk to yourdoctor about any side effect that seems unusual or that is especially bothersome e coli for insulin production.


What other drugs will affect insulin aspart?
• Many drugs can interact with insulin or affect blood sugar levels e coli for insulin production. Donot take any other medicines, including prescription products or over-the-countermedicines or supplements, without first talking to your doctor or pharmacistduring treatment with insulin e coli for insulin production.


Where can I get more information?
• Your pharmacist has additional information about insulin aspart writtenfor health professionals that you may read e coli for insulin production.


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