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insulin signaling pathway


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insulin signaling pathway
(IN suh lin AH spart)
NovoLog

What is the most important information I should know about insulin aspart?
• Know the signs and symptoms of low blood sugar (hypoglycemia), whichinclude headache, drowsiness, weakness, dizziness, fast heartbeat, sweating,tremor, and nausea insulin signaling pathway. Carry a piece of candy or glucose tablets with you to treatepisodes of low blood sugar insulin signaling pathway.
• Follow any diet and exercise plan that you have developed with your doctoror nurse insulin signaling pathway. Changes in what you eat or how much you exercise can change the amountof insulin that you need to control blood sugar levels insulin signaling pathway.
• Ask your doctor or nurse what to do if you are sick with a cold, flu,or fever insulin signaling pathway. These illnesses may change your insulin requirements insulin signaling pathway.
• Insulin aspart differs from regular human insulin by how quickly it beginsto work and the amount of time it continues to be effective insulin signaling pathway. Because insulinaspart begins to work soon after it is injected, the injection of insulin aspartshould immediately be followed by a meal insulin signaling pathway. Because of the short amount of timethat insulin aspart continues to be effective, a longer-acting insulin may alsobe required insulin signaling pathway.
• Do not change the brand of insulin aspart or syringe that you are usingwithout first talking to your doctor or pharmacist insulin signaling pathway. Some brands of insulin aspartand syringes are interchangeable, while others are not insulin signaling pathway. Your doctor and/or pharmacistknow which brands can be substituted for one another insulin signaling pathway.


What is insulin aspart?
• Insulin is a hormone naturally produced by the pancreas insulin signaling pathway. Insulin enablesthe body to use the sugar in food as a source of energy insulin signaling pathway. When the body doesnot produce enough insulin, or when the insulin produced by the body is noteffective enough, the condition is called diabetes mellitus insulin signaling pathway. This conditionallows sugar levels in the blood to become very high insulin signaling pathway. Diabetics must use man-madeinsulin or insulin that comes from pigs (which is very similar to human insulin)to lower these high blood sugar levels insulin signaling pathway.
• There are three types of insulin, which differ in how soon they beginto work and how long their effects last insulin signaling pathway. Insulin aspart is one type of insulinthat begins to work very quickly and its effects that last for approximately3 to 5 hours insulin signaling pathway. Insulin aspart is usually used in combination with another longer-actinginsulin insulin signaling pathway.
• Insulin aspart may also be used for purposes other than those listedin this medication guide insulin signaling pathway.


What should I discuss with my healthcare provider before using insulin aspart?
• Do not use insulin aspart if you are allergic to insulin or if you havean intolerance of a certain insulin aspart product insulin signaling pathway.
• Before using insulin aspart, tell your doctor if you have kidney or liverdisease insulin signaling pathway. You may require a dosage adjustment or special monitoring during treatment insulin signaling pathway.
• Insulin aspart is in the FDA pregnancy category C insulin signaling pathway. This means that itis not known whether it will be harmful to an unborn baby insulin signaling pathway. Do not use this medicationwithout first talking to your doctor if you are pregnant or could become pregnantduring treatment insulin signaling pathway.
• It is not known whether insulin aspart passes into breast milk insulin signaling pathway. Do notuse this medication without first talking to your doctor if you are breast-feedinga baby insulin signaling pathway.


How should I use insulin aspart?
• Use insulin aspart exactly as directed by your doctor insulin signaling pathway. If you do notunderstand these instructions, ask your doctor, nurse, or pharmacist to explainthem to you insulin signaling pathway.
• Insulin aspart differs from regular human insulin by how quickly it beginsto work and the amount of time it continues to be effective insulin signaling pathway. Because insulinaspart begins to work soon after it is injected, the injection of insulin aspartshould immediately be followed by a meal insulin signaling pathway. Because of the short amount of timethat insulin aspart continues to be effective, a longer-acting insulin may alsobe required insulin signaling pathway.
• Insulin aspart is usually used immediately before a meal (a meal shouldbe started within 5 to 10 minutes after injecting the medication) insulin signaling pathway. Follow yourdoctor's instructions insulin signaling pathway.
• Rotate injection sites as directed by your doctor insulin signaling pathway. Usually, you shouldnot inject within 1 inch of the same site within 1 month insulin signaling pathway.
• Never reuse a needle or syringe insulin signaling pathway. The syringes used must not contain anyother medicinal product or residue insulin signaling pathway. Dispose of all needles and syringes in anappropriate, puncture-resistant disposal container insulin signaling pathway.
• Do not change the insulin strength (e.g., U-100) or insulin type (e.g.,aspart) unless your doctor recommends a change for you insulin signaling pathway.
• Do not change the brand of insulin aspart or syringe that you are usingwithout first talking to your doctor or pharmacist insulin signaling pathway. Some brands of insulin andsyringes are interchangeable, while others are not insulin signaling pathway. Your doctor and/or pharmacistknow which brands can be substituted for one another insulin signaling pathway.
• Follow any diet and exercise plan that you have developed with your doctoror nurse insulin signaling pathway. Changes in what you eat or how much you exercise can change the amountof insulin that you need to control blood sugar levels insulin signaling pathway.
• Ask your doctor or nurse what to do if you are sick with a cold, flu,or fever insulin signaling pathway. These illnesses may change your insulin requirements insulin signaling pathway.
• Wear some type of medical identification bracelet, necklace, or otheralert tag to inform others that you have diabetes and that you require insulinin the case of an emergency insulin signaling pathway.
• To adequately control diabetes, proper foot care, eye care, dental care,and overall proper health care are necessary insulin signaling pathway. Visit your doctor, dentist, eyedoctor, and other heath care practitioners as recommended by your doctor insulin signaling pathway.
• Do not use any insulin that is discolored, looks thick, has particlesin it, or looks different from your previous bottles or cartridges of insulinaspart insulin signaling pathway.
• Store unopened bottles and cartridges of insulin aspart in the refrigeratorbetween 36 and 46 degrees Fahrenheit (2 and 8 degrees Celsius) insulin signaling pathway. Do not storeinsulin aspart in the freezer and do not allow it to freeze insulin signaling pathway. Do not use insulinaspart if it has been frozen insulin signaling pathway. Throw away any expired insulin aspart insulin signaling pathway.
• Vials or cartridges of insulin aspart in use can be kept unrefrigeratedat room temperature, below 86 degrees Fahrenheit (30 degrees Celsius), for upto 28 days but should not be exposed to excessive heat or sunlight insulin signaling pathway.


What happens if I miss a dose?
• Follow your doctor's directions if you miss a dose of insulin insulin signaling pathway. To preventmissed doses, be sure to always have enough insulin on hand, especially if youare going on vacation insulin signaling pathway.


What happens if I overdose?
• Seek emergency medical attention insulin signaling pathway.
• Symptoms of an insulin overdose reflect very low blood sugar levels andinclude headache, irregular heartbeat, increased heart rate or pulse, sweating,tremor, nausea, increased hunger, and anxiety insulin signaling pathway.


What should I avoid while using insulin aspart?
• Do not use alcohol without first talking to your doctor insulin signaling pathway. It lowers bloodsugar, and you may experience dangerously low blood sugar levels insulin signaling pathway.
• Follow any diet and exercise plan that you have developed with your doctoror nurse insulin signaling pathway. Changes in what you eat or how much you exercise can change the amountof insulin that you need to control blood sugar levels insulin signaling pathway.


What are the possible side effects of insulin aspart?
• Rarely, people have allergic reactions to insulin insulin signaling pathway. Seek emergency medicalattention if you experience an allergic reaction (difficulty breathing; closingof your throat; swelling of your lips, tongue, or face; or hives) insulin signaling pathway.
• The side effects of insulin therapy result mostly from blood sugar levelsthat are either too high or too low insulin signaling pathway. You should be familiar with the symptomsof both high and low blood sugar levels and know how to treat both conditions insulin signaling pathway. Also, be sure your family and close friends know how to help you in an emergency insulin signaling pathway.
• Low blood sugar may occur when too much insulin is used; when meals aremissed or delayed; if you exercise more than usual; during illness, especiallywith vomiting or diarrhea; if you take other medications; after drinking alcohol;and in other situations insulin signaling pathway.
• Hypoglycemia, or low blood sugar, has the following symptoms: shaking,headache, cold sweats, pale, cool skin, anxiety, and difficulty concentrating insulin signaling pathway.
• Keep sugary candy; fruit juice; or glucose tablets on hand to treat episodesof low blood sugar insulin signaling pathway.
• Increased blood sugar may occur if not enough insulin is used, if youeat significantly more food then usual, if you exercise less than usual, ifyou take other medications, if you have a fever or other illness, and in othersituations insulin signaling pathway.
• Hyperglycemia, or high blood sugar, has the following symptoms: increasedthirst, increased hunger, and increased urination insulin signaling pathway.
• Monitor your blood sugar levels and ask your doctor how to adjust yourinsulin doses if your blood sugar levels are too high insulin signaling pathway.
• Side effects may also occur at the site of injection insulin signaling pathway. If the area becomesthickened, hard, or pitted, talk to your doctor before injecting at that siteagain insulin signaling pathway.
• Side effects other than those listed here may also occur insulin signaling pathway. Talk to yourdoctor about any side effect that seems unusual or that is especially bothersome insulin signaling pathway.


What other drugs will affect insulin aspart?
• Many drugs can interact with insulin or affect blood sugar levels insulin signaling pathway. Donot take any other medicines, including prescription products or over-the-countermedicines or supplements, without first talking to your doctor or pharmacistduring treatment with insulin insulin signaling pathway.


Where can I get more information?
• Your pharmacist has additional information about insulin aspart writtenfor health professionals that you may read insulin signaling pathway.


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