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production of insulin
(IN suh lin AH spart)
NovoLog

What is the most important information I should know about insulin aspart?
• Know the signs and symptoms of low blood sugar (hypoglycemia), whichinclude headache, drowsiness, weakness, dizziness, fast heartbeat, sweating,tremor, and nausea production of insulin. Carry a piece of candy or glucose tablets with you to treatepisodes of low blood sugar production of insulin.
• Follow any diet and exercise plan that you have developed with your doctoror nurse production of insulin. Changes in what you eat or how much you exercise can change the amountof insulin that you need to control blood sugar levels production of insulin.
• Ask your doctor or nurse what to do if you are sick with a cold, flu,or fever production of insulin. These illnesses may change your insulin requirements production of insulin.
• Insulin aspart differs from regular human insulin by how quickly it beginsto work and the amount of time it continues to be effective production of insulin. Because insulinaspart begins to work soon after it is injected, the injection of insulin aspartshould immediately be followed by a meal production of insulin. Because of the short amount of timethat insulin aspart continues to be effective, a longer-acting insulin may alsobe required production of insulin.
• Do not change the brand of insulin aspart or syringe that you are usingwithout first talking to your doctor or pharmacist production of insulin. Some brands of insulin aspartand syringes are interchangeable, while others are not production of insulin. Your doctor and/or pharmacistknow which brands can be substituted for one another production of insulin.


What is insulin aspart?
• Insulin is a hormone naturally produced by the pancreas production of insulin. Insulin enablesthe body to use the sugar in food as a source of energy production of insulin. When the body doesnot produce enough insulin, or when the insulin produced by the body is noteffective enough, the condition is called diabetes mellitus production of insulin. This conditionallows sugar levels in the blood to become very high production of insulin. Diabetics must use man-madeinsulin or insulin that comes from pigs (which is very similar to human insulin)to lower these high blood sugar levels production of insulin.
• There are three types of insulin, which differ in how soon they beginto work and how long their effects last production of insulin. Insulin aspart is one type of insulinthat begins to work very quickly and its effects that last for approximately3 to 5 hours production of insulin. Insulin aspart is usually used in combination with another longer-actinginsulin production of insulin.
• Insulin aspart may also be used for purposes other than those listedin this medication guide production of insulin.


What should I discuss with my healthcare provider before using insulin aspart?
• Do not use insulin aspart if you are allergic to insulin or if you havean intolerance of a certain insulin aspart product production of insulin.
• Before using insulin aspart, tell your doctor if you have kidney or liverdisease production of insulin. You may require a dosage adjustment or special monitoring during treatment production of insulin.
• Insulin aspart is in the FDA pregnancy category C production of insulin. This means that itis not known whether it will be harmful to an unborn baby production of insulin. Do not use this medicationwithout first talking to your doctor if you are pregnant or could become pregnantduring treatment production of insulin.
• It is not known whether insulin aspart passes into breast milk production of insulin. Do notuse this medication without first talking to your doctor if you are breast-feedinga baby production of insulin.


How should I use insulin aspart?
• Use insulin aspart exactly as directed by your doctor production of insulin. If you do notunderstand these instructions, ask your doctor, nurse, or pharmacist to explainthem to you production of insulin.
• Insulin aspart differs from regular human insulin by how quickly it beginsto work and the amount of time it continues to be effective production of insulin. Because insulinaspart begins to work soon after it is injected, the injection of insulin aspartshould immediately be followed by a meal production of insulin. Because of the short amount of timethat insulin aspart continues to be effective, a longer-acting insulin may alsobe required production of insulin.
• Insulin aspart is usually used immediately before a meal (a meal shouldbe started within 5 to 10 minutes after injecting the medication) production of insulin. Follow yourdoctor's instructions production of insulin.
• Rotate injection sites as directed by your doctor production of insulin. Usually, you shouldnot inject within 1 inch of the same site within 1 month production of insulin.
• Never reuse a needle or syringe production of insulin. The syringes used must not contain anyother medicinal product or residue production of insulin. Dispose of all needles and syringes in anappropriate, puncture-resistant disposal container production of insulin.
• Do not change the insulin strength (e.g., U-100) or insulin type (e.g.,aspart) unless your doctor recommends a change for you production of insulin.
• Do not change the brand of insulin aspart or syringe that you are usingwithout first talking to your doctor or pharmacist production of insulin. Some brands of insulin andsyringes are interchangeable, while others are not production of insulin. Your doctor and/or pharmacistknow which brands can be substituted for one another production of insulin.
• Follow any diet and exercise plan that you have developed with your doctoror nurse production of insulin. Changes in what you eat or how much you exercise can change the amountof insulin that you need to control blood sugar levels production of insulin.
• Ask your doctor or nurse what to do if you are sick with a cold, flu,or fever production of insulin. These illnesses may change your insulin requirements production of insulin.
• Wear some type of medical identification bracelet, necklace, or otheralert tag to inform others that you have diabetes and that you require insulinin the case of an emergency production of insulin.
• To adequately control diabetes, proper foot care, eye care, dental care,and overall proper health care are necessary production of insulin. Visit your doctor, dentist, eyedoctor, and other heath care practitioners as recommended by your doctor production of insulin.
• Do not use any insulin that is discolored, looks thick, has particlesin it, or looks different from your previous bottles or cartridges of insulinaspart production of insulin.
• Store unopened bottles and cartridges of insulin aspart in the refrigeratorbetween 36 and 46 degrees Fahrenheit (2 and 8 degrees Celsius) production of insulin. Do not storeinsulin aspart in the freezer and do not allow it to freeze production of insulin. Do not use insulinaspart if it has been frozen production of insulin. Throw away any expired insulin aspart production of insulin.
• Vials or cartridges of insulin aspart in use can be kept unrefrigeratedat room temperature, below 86 degrees Fahrenheit (30 degrees Celsius), for upto 28 days but should not be exposed to excessive heat or sunlight production of insulin.


What happens if I miss a dose?
• Follow your doctor's directions if you miss a dose of insulin production of insulin. To preventmissed doses, be sure to always have enough insulin on hand, especially if youare going on vacation production of insulin.


What happens if I overdose?
• Seek emergency medical attention production of insulin.
• Symptoms of an insulin overdose reflect very low blood sugar levels andinclude headache, irregular heartbeat, increased heart rate or pulse, sweating,tremor, nausea, increased hunger, and anxiety production of insulin.


What should I avoid while using insulin aspart?
• Do not use alcohol without first talking to your doctor production of insulin. It lowers bloodsugar, and you may experience dangerously low blood sugar levels production of insulin.
• Follow any diet and exercise plan that you have developed with your doctoror nurse production of insulin. Changes in what you eat or how much you exercise can change the amountof insulin that you need to control blood sugar levels production of insulin.


What are the possible side effects of insulin aspart?
• Rarely, people have allergic reactions to insulin production of insulin. Seek emergency medicalattention if you experience an allergic reaction (difficulty breathing; closingof your throat; swelling of your lips, tongue, or face; or hives) production of insulin.
• The side effects of insulin therapy result mostly from blood sugar levelsthat are either too high or too low production of insulin. You should be familiar with the symptomsof both high and low blood sugar levels and know how to treat both conditions production of insulin. Also, be sure your family and close friends know how to help you in an emergency production of insulin.
• Low blood sugar may occur when too much insulin is used; when meals aremissed or delayed; if you exercise more than usual; during illness, especiallywith vomiting or diarrhea; if you take other medications; after drinking alcohol;and in other situations production of insulin.
• Hypoglycemia, or low blood sugar, has the following symptoms: shaking,headache, cold sweats, pale, cool skin, anxiety, and difficulty concentrating production of insulin.
• Keep sugary candy; fruit juice; or glucose tablets on hand to treat episodesof low blood sugar production of insulin.
• Increased blood sugar may occur if not enough insulin is used, if youeat significantly more food then usual, if you exercise less than usual, ifyou take other medications, if you have a fever or other illness, and in othersituations production of insulin.
• Hyperglycemia, or high blood sugar, has the following symptoms: increasedthirst, increased hunger, and increased urination production of insulin.
• Monitor your blood sugar levels and ask your doctor how to adjust yourinsulin doses if your blood sugar levels are too high production of insulin.
• Side effects may also occur at the site of injection production of insulin. If the area becomesthickened, hard, or pitted, talk to your doctor before injecting at that siteagain production of insulin.
• Side effects other than those listed here may also occur production of insulin. Talk to yourdoctor about any side effect that seems unusual or that is especially bothersome production of insulin.


What other drugs will affect insulin aspart?
• Many drugs can interact with insulin or affect blood sugar levels production of insulin. Donot take any other medicines, including prescription products or over-the-countermedicines or supplements, without first talking to your doctor or pharmacistduring treatment with insulin production of insulin.


Where can I get more information?
• Your pharmacist has additional information about insulin aspart writtenfor health professionals that you may read production of insulin.


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