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signs and symptoms of insulin resistance
(IN suh lin AH spart)
NovoLog

What is the most important information I should know about insulin aspart?
• Know the signs and symptoms of low blood sugar (hypoglycemia), whichinclude headache, drowsiness, weakness, dizziness, fast heartbeat, sweating,tremor, and nausea signs and symptoms of insulin resistance. Carry a piece of candy or glucose tablets with you to treatepisodes of low blood sugar signs and symptoms of insulin resistance.
• Follow any diet and exercise plan that you have developed with your doctoror nurse signs and symptoms of insulin resistance. Changes in what you eat or how much you exercise can change the amountof insulin that you need to control blood sugar levels signs and symptoms of insulin resistance.
• Ask your doctor or nurse what to do if you are sick with a cold, flu,or fever signs and symptoms of insulin resistance. These illnesses may change your insulin requirements signs and symptoms of insulin resistance.
• Insulin aspart differs from regular human insulin by how quickly it beginsto work and the amount of time it continues to be effective signs and symptoms of insulin resistance. Because insulinaspart begins to work soon after it is injected, the injection of insulin aspartshould immediately be followed by a meal signs and symptoms of insulin resistance. Because of the short amount of timethat insulin aspart continues to be effective, a longer-acting insulin may alsobe required signs and symptoms of insulin resistance.
• Do not change the brand of insulin aspart or syringe that you are usingwithout first talking to your doctor or pharmacist signs and symptoms of insulin resistance. Some brands of insulin aspartand syringes are interchangeable, while others are not signs and symptoms of insulin resistance. Your doctor and/or pharmacistknow which brands can be substituted for one another signs and symptoms of insulin resistance.

What is insulin aspart?
• Insulin is a hormone naturally produced by the pancreas signs and symptoms of insulin resistance. Insulin enablesthe body to use the sugar in food as a source of energy signs and symptoms of insulin resistance. When the body doesnot produce enough insulin, or when the insulin produced by the body is noteffective enough, the condition is called diabetes mellitus signs and symptoms of insulin resistance. This conditionallows sugar levels in the blood to become very high signs and symptoms of insulin resistance. Diabetics must use man-madeinsulin or insulin that comes from pigs (which is very similar to human insulin)to lower these high blood sugar levels signs and symptoms of insulin resistance.
• There are three types of insulin, which differ in how soon they beginto work and how long their effects last signs and symptoms of insulin resistance. Insulin aspart is one type of insulinthat begins to work very quickly and its effects that last for approximately3 to 5 hours signs and symptoms of insulin resistance. Insulin aspart is usually used in combination with another longer-actinginsulin signs and symptoms of insulin resistance.
• Insulin aspart may also be used for purposes other than those listedin this medication guide signs and symptoms of insulin resistance.

What should I discuss with my healthcare provider before using insulin aspart?
• Do not use insulin aspart if you are allergic to insulin or if you havean intolerance of a certain insulin aspart product signs and symptoms of insulin resistance.
• Before using insulin aspart, tell your doctor if you have kidney or liverdisease signs and symptoms of insulin resistance. You may require a dosage adjustment or special monitoring during treatment signs and symptoms of insulin resistance.
• Insulin aspart is in the FDA pregnancy category C signs and symptoms of insulin resistance. This means that itis not known whether it will be harmful to an unborn baby signs and symptoms of insulin resistance. Do not use this medicationwithout first talking to your doctor if you are pregnant or could become pregnantduring treatment signs and symptoms of insulin resistance.
• It is not known whether insulin aspart passes into breast milk signs and symptoms of insulin resistance. Do notuse this medication without first talking to your doctor if you are breast-feedinga baby signs and symptoms of insulin resistance.

How should I use insulin aspart?
• Use insulin aspart exactly as directed by your doctor signs and symptoms of insulin resistance. If you do notunderstand these instructions, ask your doctor, nurse, or pharmacist to explainthem to you signs and symptoms of insulin resistance.
• Insulin aspart differs from regular human insulin by how quickly it beginsto work and the amount of time it continues to be effective signs and symptoms of insulin resistance. Because insulinaspart begins to work soon after it is injected, the injection of insulin aspartshould immediately be followed by a meal signs and symptoms of insulin resistance. Because of the short amount of timethat insulin aspart continues to be effective, a longer-acting insulin may alsobe required signs and symptoms of insulin resistance.
• Insulin aspart is usually used immediately before a meal (a meal shouldbe started within 5 to 10 minutes after injecting the medication) signs and symptoms of insulin resistance. Follow yourdoctor's instructions signs and symptoms of insulin resistance.
• Rotate injection sites as directed by your doctor signs and symptoms of insulin resistance. Usually, you shouldnot inject within 1 inch of the same site within 1 month signs and symptoms of insulin resistance.
• Never reuse a needle or syringe signs and symptoms of insulin resistance. The syringes used must not contain anyother medicinal product or residue signs and symptoms of insulin resistance. Dispose of all needles and syringes in anappropriate, puncture-resistant disposal container signs and symptoms of insulin resistance.
• Do not change the insulin strength (e.g., U-100) or insulin type (e.g.,aspart) unless your doctor recommends a change for you signs and symptoms of insulin resistance.
• Do not change the brand of insulin aspart or syringe that you are usingwithout first talking to your doctor or pharmacist signs and symptoms of insulin resistance. Some brands of insulin andsyringes are interchangeable, while others are not signs and symptoms of insulin resistance. Your doctor and/or pharmacistknow which brands can be substituted for one another signs and symptoms of insulin resistance.
• Follow any diet and exercise plan that you have developed with your doctoror nurse signs and symptoms of insulin resistance. Changes in what you eat or how much you exercise can change the amountof insulin that you need to control blood sugar levels signs and symptoms of insulin resistance.
• Ask your doctor or nurse what to do if you are sick with a cold, flu,or fever signs and symptoms of insulin resistance. These illnesses may change your insulin requirements signs and symptoms of insulin resistance.
• Wear some type of medical identification bracelet, necklace, or otheralert tag to inform others that you have diabetes and that you require insulinin the case of an emergency signs and symptoms of insulin resistance.
• To adequately control diabetes, proper foot care, eye care, dental care,and overall proper health care are necessary signs and symptoms of insulin resistance. Visit your doctor, dentist, eyedoctor, and other heath care practitioners as recommended by your doctor signs and symptoms of insulin resistance.
• Do not use any insulin that is discolored, looks thick, has particlesin it, or looks different from your previous bottles or cartridges of insulinaspart signs and symptoms of insulin resistance.
• Store unopened bottles and cartridges of insulin aspart in the refrigeratorbetween 36 and 46 degrees Fahrenheit (2 and 8 degrees Celsius) signs and symptoms of insulin resistance. Do not storeinsulin aspart in the freezer and do not allow it to freeze signs and symptoms of insulin resistance. Do not use insulinaspart if it has been frozen signs and symptoms of insulin resistance. Throw away any expired insulin aspart signs and symptoms of insulin resistance.
• Vials or cartridges of insulin aspart in use can be kept unrefrigeratedat room temperature, below 86 degrees Fahrenheit (30 degrees Celsius), for upto 28 days but should not be exposed to excessive heat or sunlight signs and symptoms of insulin resistance.

What happens if I miss a dose?
• Follow your doctor's directions if you miss a dose of insulin signs and symptoms of insulin resistance. To preventmissed doses, be sure to always have enough insulin on hand, especially if youare going on vacation signs and symptoms of insulin resistance.

What happens if I overdose?
• Seek emergency medical attention signs and symptoms of insulin resistance.
• Symptoms of an insulin overdose reflect very low blood sugar levels andinclude headache, irregular heartbeat, increased heart rate or pulse, sweating,tremor, nausea, increased hunger, and anxiety signs and symptoms of insulin resistance.

What should I avoid while using insulin aspart?
• Do not use alcohol without first talking to your doctor signs and symptoms of insulin resistance. It lowers bloodsugar, and you may experience dangerously low blood sugar levels signs and symptoms of insulin resistance.
• Follow any diet and exercise plan that you have developed with your doctoror nurse signs and symptoms of insulin resistance. Changes in what you eat or how much you exercise can change the amountof insulin that you need to control blood sugar levels signs and symptoms of insulin resistance.

What are the possible side effects of insulin aspart?
• Rarely, people have allergic reactions to insulin signs and symptoms of insulin resistance. Seek emergency medicalattention if you experience an allergic reaction (difficulty breathing; closingof your throat; swelling of your lips, tongue, or face; or hives) signs and symptoms of insulin resistance.
• The side effects of insulin therapy result mostly from blood sugar levelsthat are either too high or too low signs and symptoms of insulin resistance. You should be familiar with the symptomsof both high and low blood sugar levels and know how to treat both conditions signs and symptoms of insulin resistance. Also, be sure your family and close friends know how to help you in an emergency signs and symptoms of insulin resistance.
• Low blood sugar may occur when too much insulin is used; when meals aremissed or delayed; if you exercise more than usual; during illness, especiallywith vomiting or diarrhea; if you take other medications; after drinking alcohol;and in other situations signs and symptoms of insulin resistance.
• Hypoglycemia, or low blood sugar, has the following symptoms: shaking,headache, cold sweats, pale, cool skin, anxiety, and difficulty concentrating signs and symptoms of insulin resistance.
• Keep sugary candy; fruit juice; or glucose tablets on hand to treat episodesof low blood sugar signs and symptoms of insulin resistance.
• Increased blood sugar may occur if not enough insulin is used, if youeat significantly more food then usual, if you exercise less than usual, ifyou take other medications, if you have a fever or other illness, and in othersituations signs and symptoms of insulin resistance.
• Hyperglycemia, or high blood sugar, has the following symptoms: increasedthirst, increased hunger, and increased urination signs and symptoms of insulin resistance.
• Monitor your blood sugar levels and ask your doctor how to adjust yourinsulin doses if your blood sugar levels are too high signs and symptoms of insulin resistance.
• Side effects may also occur at the site of injection signs and symptoms of insulin resistance. If the area becomesthickened, hard, or pitted, talk to your doctor before injecting at that siteagain signs and symptoms of insulin resistance.
• Side effects other than those listed here may also occur signs and symptoms of insulin resistance. Talk to yourdoctor about any side effect that seems unusual or that is especially bothersome signs and symptoms of insulin resistance.

What other drugs will affect insulin aspart?
• Many drugs can interact with insulin or affect blood sugar levels signs and symptoms of insulin resistance. Donot take any other medicines, including prescription products or over-the-countermedicines or supplements, without first talking to your doctor or pharmacistduring treatment with insulin signs and symptoms of insulin resistance.

Where can I get more information?
• Your pharmacist has additional information about insulin aspart writtenfor health professionals that you may read signs and symptoms of insulin resistance.

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